Case Report

A rare case report on pediatric shellfish allergy

Betsy Mathew* and Ananta Jois

Published: 23 November, 2020 | Volume 3 - Issue 1 | Pages: 056-057

Shellfish are extensively consumed worldwide because of their nutritional value. In general they are good sources of low-fat protein rich in several essential vitamins and minerals as well as in the essential nutrients omega-3 long-chain polyunsaturated fatty acids (n-3 LCPUFAs) [1]. Shellfish belongs to “The Big 8” food groups causing allergy, which often does not outgrow during childhood. However, increase in IgE – mediated sea food allergy has been linked to shellfish. Seafood- associated shellfish include crustaceans & molluskans [2]. These may cause mild local symptoms & lead to severe systemic anaphylactic reactions by ingestion, inhalation, or contact. Globally, the prevalence of shellfish allergy estimated to be 0.5% to 2.5% of the general population [3]. There are limited data showing the prevalence of shellfish allergy in children.

A study on US pediatric population showed 1.3% of shellfish allergy. Children were more allergic to crustacean (1.2%) than mollusks (0.5%) [4]. Tropomyosin is the major allergen.

Read Full Article HTML DOI: 10.29328/journal.japch.1001018 Cite this Article Read Full Article PDF


  1. Bernstein AS, Oken E, de Ferranti S. Council on Environmental Health; Committee on Nutrition. Fish, Shellfish, and Children’s Health: An Assessment of Benefits, Risks, and Sustainability. Pediatrics. 2019; 143: e20190999. PubMed: https://pubmed.ncbi.nlm.nih.gov/31110165/
  2. Khora S. Seafood-Associated Shellfish Allergy: A Comprehensive Review. Immunological Investigations. 2016; 45: 504-530. PubMed: https://pubmed.ncbi.nlm.nih.gov/27404324/
  3. Woo C, Bahna S. Not all shellfish "allergy" is allergy!. Clinical and Translational Allergy. 2001.
  4. Wang H, Warren C, Gupta R, Davis C. Prevalence and Characteristics of Shellfish Allergy in the Pediatric Population of the United States. J Allergy Clin Immunol Pract. 2020; 8: 1359-1370e2. PubMed: https://pubmed.ncbi.nlm.nih.gov/31917365/
  5. Lopata A, O'Hehir R, Lehrer S. Shellfish allergy. Clinical & Experimental Allergy. 2010; 40: 850-858. PubMed: https://pubmed.ncbi.nlm.nih.gov/20412131/


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