Letter to Editor

Effect of preterm premature rupture of membranes on neurodevelopmental outcome of infants among preterm infants born at Hawassa comprehen sive specialized Hospital of Sidama Region, Ethiopia, 2022

Kaleab Tesfaye Tegegne*, Abiyu Ayalew Assefa, Medhin Geta, Andualem Zenebe, Wosenyeleh Semeon Bagajjo, Musie Rike and Belayneh Feleke Weldeyes

Published: 11 November, 2021 | Volume 4 - Issue 1 | Pages: 114-116

Objective: To verify whether preterm premature rupture of membranes has effect on neurodevelopmental outcome of Infant among preterm infants born at Hawassa Comprehensive Specialized Hospital of Sidama region, Ethiopia, 2022.
Methods and materials: A prospective cohort study design will be conducted for 2 years and 6 months from March 1/2022 to August 30/2024. A total of 12 Midwives. 6 supervisors and 1 pediatric neurologist or psychiatrist will be involved in the data collection process. All preterm infants will be recruited consecutively from preterm infants admitted to neonatal intensive care unit from March 1/2022 to August 30/2022. The preterm infants will be categorized into Exposed group (preterm infants born after preterm PROM) and non-exposed group (preterm infants born after spontaneous preterm labour) and followed until 2 years of age to assess neurodevelopmental outcome of infants The data will be entered into Epidata software and exported to SPSS software for windows version 23. For analysis. Descriptive statistics will be computed. One-way Anova and post hoc comparisons with Scheffe’s procedure will be used X2 test or Fisher’s exact test will be used to compare categorical variables.

Read Full Article HTML DOI: 10.29328/journal.japch.1001043 Cite this Article Read Full Article PDF


Preterm premature rupture of membranes; Neurodevelopmental outcome of Infant


  1. Caughey AB, Robinson JN, Norwitz ER. Contemporary diagnosis and management of preterm premature rupture of membranes. Rev Obstet Gynecol. 2008; 1: 11-22. https://pubmed.ncbi.nlm.nih.gov/18701929/
  2. De Jong SE, Groenendaal F, van Bel F, Rademaker KJ. Pulmonary effects of neonatal hydrocortisone treatment in ventilator-dependent preterm infants. Int J Pediatr. 2011; 2011: 783893. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250043/
  3. Balasundaram P, Avulakunta ID. Bayley Scales of Infant and Toddler Development. [Updated 2020 Dec 24]. In: StatPearls. 2021. https://www.ncbi.nlm.nih.gov/books/NBK567715/


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